Projects - Relevant Papers

• Modulation of Endocrine Pancreas Development but not B-Cell Carcinogenesis by Sprouty4
  Jaeggi F, Cabrita MA, Perl A-K, Christofori G
  Mol Cancer Res (2008) 6:468-482

• EMT, the cytoskeleton, and cancer cell invasion
  Yilmaz M, Christofori G
  Cancer Metastasis Rev (2009) 28:15-33

• Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling
  Daniels MA, Teixeiro E, Gill J, Hausmann B , Roubaty D, Holmberg K, Werlen G, Hollaender GA, Gascoigne NRJ, Palmer E
  Nature (2006) 444:724-729

• Transcriptional networks in developing and mature B cells
  Matthias P, Rolink AG
  Nat Rev Immunol (2005) 497-508

• PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos
  Puschendorf M, Terranova R, Boutsma E, Mao X, Isono K-i, Brykczynska U, Kolb K, Otte AP, Koseki H, Orkin SH, van Lohuizen M, Peters AHFM
  Nat Gen 40 (2008) 4:411-420

• Protein demethylation required for DNA methylation
  Hotz HR, Peters AHFM
  Nat Gen (2009) 41:10-11

• Rules for Gene Usage Inferred from a Comparison of Large-Scale Gene Expression Profiles of T and B Lymphocyte Development
  Hoffmann R, Bruno L, Seidl T, Rolink A, Melchers F
  J Immunol (2003) 170:1339-1353

• Genetics and epigenetics: stability and plasticity during cellular differentiation
  Mohn F, Schübeler D
  Trends Genet. (2009) 25(3):129-36

• Lineage-Specific Polycomb Targets and De Novo DNA Methylation Define Restriction and Potential of Neuronal Progenitors
  Mohn F, Weber M, Rebhan M, Roloff TC, Richter J, Stadler MB, Bibel M, Schübeler D
  Mol Cell. (2008) 30(6):755-66

• Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
  Weber M, Davies J, Wittig D, Oakeley EJ, Haase M, Lam WJ, Schübeler D
  Nature Genetics (2005) 37: 863-862

• Finding regulatory elements and regulatory motifs: a general probabilistic framework
  van Nimwegen E
  BMC Bioinformatics, 8 Suppl. 6, p 4

• SPA: A Probabilistic Algorithm for Spliced Alignment
  van Nimwegen E, Paul N, Sheridan N, Zavolan M
  PLoS Genet (2006) 2:e24

• A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing
  Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M et al.
  Cell (2007) 129:1401-1414